coagulans DSM 32016 during common pelleting conditions, which makes TechnoSpore® an appropriate candidate for a broad range of applications.įigure 2 : Average relative zootechnical performance recorded in 17 broiler trials with a control group and a group fed B. This test successfully demonstrated a reliable heat resistance of B. In a pelleting test, including temperatures between 80☌ and 100☌, the recovery rate of Bacillus coagulans DSM 32016 in TechnoSpore® was investigated. It is well known that untreated lactic acid bacteria are not heat stable and thus not suitable for thermal feed treatments. coagulans DSM 32016 have been measured, towards gram-positive as well as gram-negative pathogens.įor feed application another important aspect needs to be considered: heat stability. Next to this, direct inhibition effects of B. The reliable lactic acid production capacity of Bacillus coagulans DSM 32016 resulted in a reduction of pH, which exemplary shows the beneficial potential of administered B. An in vitro study demonstrated that bacterial species differ strongly in their efficiency to produce lactic acid (Figure 1). Based on Bacillus coagulans DSM 32016, a novel feed additive with the brand name “TechnoSpore®” has been approved by the EU under the Feed Additives Regulation (Regulation (EC) No 1831/2003).įigure 1: Efficiency of lactic acid production of different probiotics in vitro (Data collection by Biochem, 2018).Īccording to the product development team of Biochem Zusatzstoffe (Lohne, Germany), this new probiotic strain is a unique 2 in 1 solution that combines the advantages of spore-forming bacteria and lactic acid- producing bacteria to beneficially modulate the intestinal microbiota. Such observations have led to the idea for the development of a new probiotic. Recent studies showed that the microbiota thrives, and performance is enhanced when animals are fed with a combination of lactic-acid producing and spore- forming bacteria. The development of effective probiotics and unraveling their mode of action is a continuous topic of research. In contrast to LAB, only spore-forming Bacillus probiotics are naturally heat resistant, which is an essential technical feature to ensure the use in pelleted feed. Also, spore-forming strains are known to have a substantial beneficial effect on gut health of poultry mainly based on enzyme production, direct inhibition of certain pathogens via bioavtive peptides, and achievement of a favorable environment for other health- beneficial bacteria such as LAB. A welldocumented probiotic class are lactic acid bacteria (LAB), known to positively modulate the intestinal microbiota by inhibiting pathogens in the gut and maintaining the intestinal barrier function. These differences directly impact the selection of a suitable probiotic depending on the intended purpose. The available probiotic categories differ from each other in terms of properties and mode of action. The portfolio of probiotics available on the market today is growing remarkably. They are known to be one of the most successful groups of gut health-promoting supplements. Probiotics are live microorganisms that may beneficially affect the host upon ingestion by improving or maintaining the balance of the intestinal microbiota. Today probiotics are increasingly used in commercial livestock farming to stabilize gastrointestinal function and thereby improve animal health and productivity. In this regard, it is crucial to support and modulate the microbiota in such a way that it is strengthened to fight unwanted bacteria such as Salmonella, E. If this balance is disturbed due to factors such as environmental stress or dietary impacts, a reduced performance or increased susceptibility to infections are frequent consequences. A well-balanced gut microbiota plays an essential role in protecting the bird against inappropriate overgrowth of pathogens, other harmful bacteria, and viruses. The gut is a very dynamic and smart ecosystem on its own, colonized by a complex community of highly diverse microbes. Therefore an important key for keeping poultry healthy under modern production conditions, is to take care of the health associated to the gastro intestinal tract. A healthy gut system is vital for proper digestion of feed, good growth performance, and the prevention of several digestive disorders such as necrotic enteritis.
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